I started on Trelegy around the 1st of the year and it has been amazing! I feel 100% normal ever since starting on this drug and have had zero issues with it. I just thought I would give this perspective to anybody who may be thinking of trying it. I get mine thru a Canadian pharmacy at a fraction of the cost in the U.S., even with my insurance coverage. That being said, I may try going back to Spiriva soon so to see if I stay the same or go backwards, but I will admit, I'm a bit leery of changing anything at this point.