Again, I am relatively new to COPD and trying to learn as I go. I only use Spiriva as a maintenance medication and Pro Air as a rescue inhaler. My husband and I were able to take our vacation out west and I did OK dealing with the higher altitudes. We definitely avoided some areas/parks because of altitude, but thoroughly enjoyed our vacation. I was on a boost of Prednisone in early September along with a 10 day antibiotic. I felt fine. Upon returning to MI, I felt the return of the chocking sensation as well as increased mucus and started another course of prednisone. I was using my rescue inhaler about every 4-5 hours for SOB. I went to my PCP a week after returning, explained what was going on, and she prescribed Advair, 2 puffs twice a day. I tried that for 2 days and felt like the mucus was much thicker and more difficult to dislodge. I am following up with mu pulmonologist next week, but wondered what experiences others have had with Advair.